Mesothelioma Symptoms: An Overview

By Eric Morris

Malignant mesotheliomas are rare cancers that form in the tissues lining the lungs (pleura), abdomen (peritoneum) or heart (pericardium). Pleural mesothelioma, which affects the lining of the lungs, is the most common, accounting for about 75 percent of all malignant mesotheliomas. Between ten and twenty percent of all malignant mesotheliomas are peritoneal mesotheliomas. Pericardial mesotheliomas are extremely rare. A history of exposure to asbestos is found in most individuals with mesothelioma. The time from exposure to onset of cancer may be as long as thirty years; this is why most people with malignant mesothelioma are between 50 and 70 years old.

Many symptoms of malignant mesothelioma are non-specific, and are also seen in a number of other chest and abdominal conditions. This, combined with the lack of an accurate history of asbestos exposure in some patients, may considerably delay diagnosis. The majority of people with mesothelioma only have symptoms during the two to three months before they are diagnosed. About one quarter of all people with malignant mesothelioma have symptoms for about six months before diagnosis.



Once symptoms are present, they may depend on the location of the primary cancer. In general, symptoms become more pronounced with more advanced disease. With pleural mesothelioma, common symptoms are difficulty breathing, cough, pain in the chest or under the ribcage, coughing up blood, hoarseness, and the collection of fluid or pleural effusion in the pleural cavity. The face and arms may swell up. Many of these symptoms and signs are also seen with lung cancer.

With peritoneal mesothelioma, symptoms may include a lump or swelling in the abdomen, abdominal pain, fluid in the abdomen, constipation due to bowel obstruction, nausea, vomiting, and loss of appetite. Patients suffering from pericardial mesothelioma may experience chest pain, breathlessness and palpitations. Some symptoms of malignant mesothelioma are common to many cancers. These include unexplained weight loss, fever and fatigue.


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Mesothelioma Treatment Stages

By Marcus Peterson

Mesothelioma is the term used for a cancerous tumor, which involves the mesothelioma cells of lungs, heart or abdominal organs. Medical specialists in mesothelioma provide treatment to the patients after assessing the stage of the mesothelioma in their specific case. They analyze the location of the cancer, the level to which it is spread and the patient?s age and general health condition.

Malignant mesothelioma is a disease in which the malignant cells are found in the sac that lines the chest or abdomen. There are four stages of malignant mesothelioma. The first stage is localized mesothelioma and the remaining three are considered advanced stages of mesothelioma. Localized mesothelioma is the phase wherein the cancer is discovered in the lung, diaphragm or in the lining of the chest cavity. The patients in their first stage of mesothelioma get their cancer surgically removed by pleurectomy or decortication or extrapleural pneumonectomy.

In the second stage, the cancer is detected to have spread beyond the lining of the chest cavity. In the third stage, the tumor growth spreads into several areas that include chest wall, center of the chest, heart, and throughout the diaphragm. The treatment in the second, third and fourth stages of mesothelium are done in tandem with supportive care. The treatment for these advanced stages focuses on providing a patient with relief from symptoms, as total cure is generally not achieved. The treatment methodology includes thoracentesis that removes fluid accumulation in the chest cavity, operations to remove the tumor and radiation therapy or chemotherapy aimed at easing symptoms.

In the fourth stage, the cancer is in the process of distant metastasis, which implies that it has spread to other organs and tissues far from its site of origin in the pleural, peritoneal, or pericardial mesothelium. Patients suffering from the fourth stage should enroll themselves in clinical trials that evaluate the newest treatment possibilities in large medical centers. Pain management is an essential aspect of the care of such patients. It is important for patients to know that medications are available to effectively treat pain due to mesothelioma. They should request pain medications or discuss pain control problems with their cancer care team.


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